Among micronutrients, calcium (Ca) and inorganic (i) phosphate (P) are the two main constituents of hydroxyapatite, the bone mineral that strengthens the mech . The acquisition and maintenance of bone mass and strength are influenced by environmental factors, including physical activity and nutrition. Among micronutrients, calcium (Ca) and ...
دردشة على الإنترنت Read MoreCalcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their discovery in the 1980s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering.
دردشة على الإنترنت Read More2014-1-1 CPCs, on the other hand, are considered an excellent synthetic material to fill bone cavities, defects or discontinuities. 4, 5 This is because they are biocompatible and osteoconductive mouldable or injectable pastes that are able to self-set in a bone cavity, 6 thereby avoiding the use of preformed materials that are designed to fit the surgical site around the implant and machine the graft to the cavity shape, which can lead to increase in bone
دردشة على الإنترنت Read More2017-12-20 Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their discovery in the 1980s, extensive research has been conducted to
دردشة على الإنترنت Read More2020-2-29 Human bone comprises of about 70% of calcium phosphate (CaP) mineral, therefore CaPs are possible alternative materials to fix a broken bone. CaP is broadly utilized for bone fixation because of its bioactive properties like osteoinductivity, osteoconductivity, and biodegradability.
دردشة على الإنترنت Read More2021-2-19 Currently, the global orthobiologics market could be segmented into the demineralized bone matrix (DBM), allograft, bone morphogenetic protein (BMP) and artificial bone graft substitutes, in which...
دردشة على الإنترنت Read More2021-6-15 Calcium hydroxyapatite (HA) and beta tri-calcium phosphate (β-TCP), which belong to the calcium phosphate ceramics group, are bio-compatible osteo-conductive materials which offer a chemical environment and a surface conducive to new bone formation. 3 – 6 Their efficacy as substitutes for autologous graft in filling bone defects have been proved by various clinical as well as experimental
دردشة على الإنترنت Read More2019-1-14 Calcium is one of the ions that form the bone matrix, and it exists mostly in the form of calcium phosphates in bone tissues [ 28 ]. These calcium ions cause bone formation and maturation through calcification. In addition, calcium ions affect bone regeneration through cellular signaling.
دردشة على الإنترنت Read More2019-7-19 Bone calcium:A vast majority of body calcium is in bone. Within bone, 99% of the calcium is tied up in the mineral phase, but the remaining 1% is in a pool that can rapidly exchange with extracellular calcium. As with calcium, the majority of body phosphate (approximately 85%) is present in the mineral phase of bone.
دردشة على الإنترنت Read More2020-2-29 Human bone comprises of about 70% of calcium phosphate (CaP) mineral, therefore CaPs are possible alternative materials to fix a broken bone. CaP is broadly utilized for bone fixation because of its bioactive properties like osteoinductivity, osteoconductivity, and biodegradability.
دردشة على الإنترنت Read MoreThe phosphate ions in calcium phosphate likely react with hydrochloric acid in the stomach to neutralize the pH. In toothpaste and in systemic circulation, calcium phosphate provides a source of calcium and phosphate ions to support remineralization of the teeth and bone homeostasis respectively. The increase in plasma calcium reduces calcium flux from osteocyte activity by reducing the ...
دردشة على الإنترنت Read More2018-1-9 Calcium phosphate (CaP) is an ideal bone substitutive material that is widely used for bone repair due to its excellent biological properties including osteoinductivity, osteoconductivity and biodegradability. For this reason, investigation of these properties and the effects of various influencing factors is vital for modulating calcium ...
دردشة على الإنترنت Read More2019-1-14 Conclusion: Calcium phosphate has been used for bone regeneration in various forms such as coating, cement and scaffold based on its unique bioactive properties and bone regeneration effectiveness. Additionally, several studies have been actively carried out to improve the efficacy of calcium phosphate in combination with various healing agents.
دردشة على الإنترنت Read More2008-11-12 Bioinorganic supplementation of calcium phosphate-based bone substitutes to improve in vivo performance: a systematic review and meta-analysis of animal studies. Biomaterials Science 2020, 8 (17) , 4792-4809.
دردشة على الإنترنت Read More2015-4-20 Objective: The purpose of this study was to review the current status of calcium phosphate (CaP) scaffolds combined with bone morphogenetic proteins (BMPs) or mesenchymal stem cells (MSCs) in the field of bone tissue engineering (BTE).. Date Sources: Data cited in this review were obtained primarily from PubMed and Medline in publications from 1979 to 2014, with highly regarded older ...
دردشة على الإنترنت Read MoreCalcium phosphate cements have been the subject of many studies in the last decade because of their biocompatibility, their capacity to fill bone cavities and their hardening properties; properties which are desirable in a broad range of surgical applications. The setting and hardening of these materials are controlled by dissolution–precipitation chemical reactions at room or body ...
دردشة على الإنترنت Read More2012-8-28 Results and Discussion. To investigate the relationship between intracellular calcium phosphate accumulations and extracellular bone apatite formation, we cultured mouse calvarial osteoblasts and marrow stromal cells (MSC) in osteogenic medium according to standard in vitro methods for bone-like nodule formation ().We have previously demonstrated by multivariate analyses
دردشة على الإنترنت Read MoreCalcium is a mineral that is found throughout the body. It makes up, together with phosphate, the main strength in the bones. Calcium is also used to help ‘power’ muscles, and is carried around the body in the blood. The blood calcium level must be kept very tightly controlled for the body to work normally, and PTH is important in this.
دردشة على الإنترنت Read More2014-2-1 Phosphate plays an important role in structural support and soft tissue. It is the major component of hydroxyapatite in bone, whereas the phosphate found in soft tissue is cellular in nature. Although phosphate can be found in organic and inorganic forms, only levels of the inorganic form can be measured in the clinical laboratory.
دردشة على الإنترنت Read More2020-2-29 Human bone comprises of about 70% of calcium phosphate (CaP) mineral, therefore CaPs are possible alternative materials to fix a broken bone. CaP is broadly utilized for bone fixation because of its bioactive properties like osteoinductivity, osteoconductivity, and biodegradability.
دردشة على الإنترنت Read More2008-11-12 Bioinorganic supplementation of calcium phosphate-based bone substitutes to improve in vivo performance: a systematic review and meta-analysis of animal studies. Biomaterials Science 2020, 8 (17) , 4792-4809.
دردشة على الإنترنت Read More2019-1-14 Conclusion: Calcium phosphate has been used for bone regeneration in various forms such as coating, cement and scaffold based on its unique bioactive properties and bone regeneration effectiveness. Additionally, several studies have been actively carried out to improve the efficacy of calcium phosphate in combination with various healing agents.
دردشة على الإنترنت Read More2018-11-9 Calcium phosphate coatings, 14 Application methods, 15 Quality assessment of calcium phosphate coatings, 16 BONE IMPLANT INTERFACE BIOLOGY, 19 Bone structure and function, 19 Bone healing/repair around implants, 19 Local enhancement of bone repair, 21 Biological response to calcium phosphate coatings, 21
دردشة على الإنترنت Read More2015-4-20 Objective: The purpose of this study was to review the current status of calcium phosphate (CaP) scaffolds combined with bone morphogenetic proteins (BMPs) or mesenchymal stem cells (MSCs) in the field of bone tissue engineering (BTE).. Date Sources: Data cited in this review were obtained primarily from PubMed and Medline in publications from 1979 to 2014, with highly regarded older ...
دردشة على الإنترنت Read MoreCalcium phosphate cements have been the subject of many studies in the last decade because of their biocompatibility, their capacity to fill bone cavities and their hardening properties; properties which are desirable in a broad range of surgical applications. The setting and hardening of these materials are controlled by dissolution–precipitation chemical reactions at room or body ...
دردشة على الإنترنت Read MoreCalcium is a mineral that is found throughout the body. It makes up, together with phosphate, the main strength in the bones. Calcium is also used to help ‘power’ muscles, and is carried around the body in the blood. The blood calcium level must be kept very tightly controlled for the body to work normally, and PTH is important in this.
دردشة على الإنترنت Read MoreCalcium phosphate cement (CPC) can conform to complex bone cavities and set in-situ to form bioresorbable hydroxyapatite. The aim of this study was to develop a CPC-collagen composite with improved fracture resistance, and to investigate the effects of
دردشة على الإنترنت Read MoreThe role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation Suwimon Boonrungsimana, Eileen Gentlemana,b,c, Raffaella Carzanigad, Nicholas D. Evansa,b,1, David W. McComba,e, Alexandra E. Portera,2, and Molly M. Stevensa,b,f,2 Departments of aMaterials and fBioengineering, bInstitute of Biomedical Engineering, and dElectron Microscopy Centre, Division of
دردشة على الإنترنت Read More2014-2-1 Phosphate plays an important role in structural support and soft tissue. It is the major component of hydroxyapatite in bone, whereas the phosphate found in soft tissue is cellular in nature. Although phosphate can be found in organic and inorganic forms, only levels of the inorganic form can be measured in the clinical laboratory.
دردشة على الإنترنت Read More